ALLERGY, RESPIRATORY
Obesity May Raise Kids' Allergy Risk
Molecule in Skin May Link Eczema and Asthma
Know Your Asthma Triggers
ALTERNATIVE MEDICINE
Massage Fosters Healing in Bereaved Relatives
U.S. Spends Billions On Alternative Medicine
Licorice May Block Absorption of Organ Transplant Drug
ANIMAL CARE
Safe Toys for Dogs
Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe
Animals Respond to Acupuncture's Healing Touch
BONES & JOINTS
Majority of College Students Report Backpack-Related Pain
Weight Loss Might Not Curb Knee Arthritis
Put Your Best Foot Forward Next Year
CANCER
Multiple Screening Strategy Boosts Cervical Cancer Detection
Mineral May Reduce High-Risk Bladder Disease
HPV Vaccine Has Higher Allergic Reaction Rate
CAREGIVING
Mild Flu Season Coming to a Close
Tainted China Formula Caused High Rate of Kidney Stones in Kids
TV Watching Doesn't Fast-Track Baby's Skills
CIRCULATORY SYSTEM
Varicose Veins May Mask Larger Problem
Walk 100 Steps a Minute for 'Moderate' Exercise
Laughter Can Boost Heart Health
COSMETIC
Health Tip: After Liposuction
Contact Lenses Boost Kids' Self-Image
Study Evaluates Laser Therapies for Hair Removal
DENTAL, ORAL
Toothbrushing May Stave Off Heart Woes
Rheumatoid Arthritis May Harm Gums
Good Oral Hygiene May Protect Against Heart Infections
DIABETES
Study Shows Turmeric May Prevent Type 2 Diabetes
Poor Blood Sugar Control After Heart Surgery Impacts Outcomes
Fish Twice a Week Cuts Diabetics' Kidney Risks
DIET, NUTRITION
School Meals Need to Get Healthier
Many Cancer Survivors Don't Adopt Healthy Lifestyle
Occaisonal Dieting May Cut Breast Cancer, Study Says
DISABILITIES
Could Your Cell Phone Help Shield You From Alzheimer's?
Review Finds Marijuana May Help MS Patients
ENVIRONMENTAL HEALTH
Seasons Arriving 2 Days Earlier, Study Says
'Safe' Ozone Levels May Not Be for Some
Climate Change Could Sting Allergy, Asthma Sufferers
EYE CARE, VISION
Blood Sugar Control Helps Diabetics Preserve Sight
Diabetic Hispanics Missing Out on Eye Exams
Contact Lens Cases Often Contaminated
FITNESS
Good Warm-Ups Could Halve Sports Injuries
Simple Steps Get Walkers Moving
School Phys. Ed. Injuries Up 150 Percent
GASTROINTESTINAL PROBLEMS
New Yogurt May Ease Stomach Ulcers
Intestinal Bacteria Trigger Immune Response
Traditional Nonsurgical GERD Treatments Not Impressive
GENERAL HEALTH
Most Women Struggle With Rising Health Care Costs
Want Better Health in the New Year, Add Exercise to Your Day
A Honey of a Sinusitis Treatment
HEAD & NECK
Many Children Will Outgrow Headaches
Zen May Thicken Brain, Thwart Pain
Ski Helmets Encouraged for All
HEALTH & TECHNOLOGY
E-Mailing Your Way to Healthier Habits
Imaging Sheds Light on How Acupuncture Works
'Cell Phone Elbow' -- A New Ill for the Wired Age
HEARING
Noise Hurts Men's Hearing More, Study Shows
Summer Sounds Can Lead to Hearing Loss
HEART & CARDIOVASCULAR
Quitting Smoking Doubles Survival in Early Stage Lung Cancer
Dark Chocolate May Lower Stroke Risk
Heart Disease May Be Prevented By Taking Fish Oils, Study Shows
INFECTIOUS DISEASE
Viral Infection Might Trigger High Blood Pressure
Older Adults May Have Some Immunity to Swine Flu
Surgical Masks Could Prevent Flu, Maybe
INFERTILITY
Obesity May Affect Fertility in Young Womene
KID'S HEALTH
Treat Kids to a Safe Halloween
Bullying Seems to Affect Kids Years Later
6 Million U.S. Kids Lack Enough Vitamin D
MEN'S HEALTH
Low Vitamin D Levels May Boost Men's Heart Attack Risk
Lots of Sex May Prevent Erectile Dysfunction
More Vitamin C May Mean Less Chance of Gout
MENTAL HEALTH
Mind Exercise Might Help Stroke Patients
A Simple 'Thank You' Brings Rewards to All
The 3LS Wellness Program for Reversing Chronic Symptoms and Creating Lasting Health
PHYSICAL THERAPY
PREGNANCY
Exercise As Well As Acupuncture, May Ease Polycystic Ovarian Syndrome
Acupuncture May Ease Depression During Pregnancy
Mom's Extra Pregnancy Pounds May Raise Child's Heart Risks
SENIORS
Community Exercise Programs Boost Seniors' Strength
Seniors Who Volunteer May Live Longer
Mediterranean Diet Plus Exercise Lowers Alzheimer's Risk
SEXUAL HEALTH
SLEEP DISORDERS
Lose Weight, Sleep Apnea May Improve
Exercising Throat Muscles May Relieve Sleep Apnea
Sleeping Could Help Women Lose The Baby Fat
WOMEN'S HEALTH
Mom and Baby Alike May Benefit From Exercise
Heal Your Life® Tips for Living Well
Exercise During Pregnancy Keeps Newborn Size Normal
Add your Article

Clues Found to Brain Mechanism Behind Migraines

WEDNESDAY, March 11 (HealthDay News) -- Scientists believe they may have found the biological trigger to a particular type of migraine headache.

In the March 12 issue of Neuron, an Italian university study on mice found that increased levels of the neurotransmitter glutamate in the brain appear to kick off a cortical spreading depression (CSD), a phenomenon that causes migraine sufferers to experience a visual disturbance known as migraine aura. The mice in the study had a gene mutation that has been shown to make people more susceptible to familial hemiplegic migraine (FHM), a subtype of severe migraine accompanied by the aura.

Brain imaging has previously shown that strong neuronal depolarization creeps across the cerebral cortex during CSD, initially increasing electrical signals in the brain, then suppressing neural activity for an extended period of time. Researchers have suspected CSD may flip on certain switches that start a migraine headache.

The researchers from the University of Padova, led by senior author Daniela Pietrobon, found that calcium influx and subsequent glutamate release at cortical pyramidal cell synapses were greater in mice with the FHM mutation. When the release of glutamate -- the major excitatory neurotransmitter in the brain -- was decreased to normal levels, the mice did not experience aura-inducing CSD.

"Our findings provide direct evidence that enhanced glutamate release may explain the facilitation of CSD in the FHM mouse model," Pietrobon, who works in the university's biomedical sciences department, said in a news release issued by the journal's publisher.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about migraines.



-- Kevin McKeever



SOURCE: Cell Press, news release, March 11, 2009

Last Updated: March 11, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

More articles at www.eholistic.com